Separex - Supercritical Fluid Technology

Michel PERRUT

President & C.E.O.

PhD - Chemical Engineering

After a PhD thesis on liquid-liquid extraction and 7 years as R&D scientist in the oil refining industry, Michel became professor of Process Engineer at the Ecole Nationale Supérieure des Industries Chimiques (Institut Polytechnique de Lorraine) which he chaired for 4 years (1979-1983) and where he founded a laboratory on Supercritical Fluid applications (extraction/fractionation/chromatography).
In 1985, he founded SEPAREX as a start-up company dedicated to separation science. In parallel, he created the International Society for the Advancement of Supercritical Fluids (www.isasf.net) that is used to organize and/or sponsor symposia, meetings and seminars worldwide. He authored about 150 publications or communications and 25 patent applications.




Jean-Yves CLAVIER

SEPAREX Equipment Manager

PhD - Process Engineering, Master-Management and Strategic Planning

Bringing a multi-facet scientific education in mechanics, biotechnology and process engineering and a first experience in a large research centre working on toxic waste treatment, Jean-Yves came in SEPAREX for developing SCF preparative chromatography and particularly continuous chromatography in 1992. He joined the “equipment” team when SEPAREX designed their first SFE production plants and took progressively the responsibility of the activity. He developed this activity bringing professional methods of construction, focusing on clean and high quality equipment, innovative high pressure tools and close collaboration between users and system designers.




Frantz DESCHAMPS

SEPAREX Pharmaceutical Technology Manager

PhD - Pharmaceutical Sciences

Frantz began his career as a researcher within the Lavipharm Group, focusing on lipid-based drug delivery systems and supercritical fluid technology. Prior to joining Separex, he spent three years in R&D project management at Mainelab, a drug delivery company subsidiary of the Ethypharm group, primarily concentrated on the development of innovative formulation techniques for the delivery of therapeutic proteins and poorly-soluble drugs. Frantz has been with Separex since 2004 and focuses on developing the Separex supercritical technology platform into state-of-the-art pharmaceutical development tools for Separex partners.




Eric FRANCAIS

Process Development Project Manager

PhD - Chemical Engineering

After a first experience in the chemical industry, Eric joined Separex in 1995 and then focused on the development of supercritical processes applications in various domains such as extraction of natural products (e.g. aromas, lipids...), purification and fractionation of polymers (e.g. lubricants for hard disks), inorganic chemistry (e.g. catalysts dewaxing, aerogels drying), cleaning of mechanical (wafers and micro-electronics industry) and optical devices.




Fabrice LEBOEUF

Pharmaceutical Technology Project Manager

PhD - Chemical Engineering

Since his arrival at Separex in 2000, Fabrice developed APIs processing using supercritical fluids. He is leading projects dealing more specifically with small molecules : size, morphology and polymorphic form tuning. Fabrice also acquired expertise in cGMP-compliant equipment design, clean environments (clean-rooms, isolators) and handling of high potent compounds.




Jennifer JUNG

Pharmaceutical Technology Project Manager

PhD - Process engineering

After her degree in Biochemical Science and various experiences in biotechnological research centers, Jennifer came to Separex in 1997 to set up and develop supercritical processes applications in the pharmaceutical domain. Primarily concentrated on the development of innovative processes for therapeutic drugs micronization, she focuses now on process development for biopharmaceuticals formulation.




Delphine QUINIOU

Analytical Laboratory manager

M.Sc. - Analytical Chemistry and Applied Statistics

Prior to joining SEPAREX in 2007, Delphine gathered a solid grounding in analytical chemistry within several analytical facilities, then worked as a research chemist at a biopharmaceutical CRO (Biotec Centre). She is committed to develop and validate analytical methods for the characterization of APIs and innovative pharmaceutical formulations.